HOMA-IR Calculator for Insulin Resistance
The HOMA-IR is being used extensively for estimates of beta cell function and insulin resistance, both in clinical practice and studies, with the caveat that it cannot be used on patients on insulin.
The QUICKI (Quantitative Insulin Sensitivity Check Index) model determines the subject’s level of insulin sensitivity, which is the opposite of insulin resistance. This estimation is preferred for its simplicity to the glucose clamp and the minimal model analysis.
HOMA-IR Calculator for Insulin Resistance
HOMA-IR = (Fasting insulin in mIU/L x Fasting glucose in mg/dL) / 405
HOMA-IR Interpretation
Normal reference levels for HOMA-IR range between 0.7 and 2.0. Several studies use the 2.0 value as cut-off for increased insulin resistance.
QUICKI = 1 / [log(Fasting insulin in mIU/L) + log(Fasting glucose in mg/dL)]
QUICKI Interpretation
- >0.45: normal reference level;
- 30 - 0.45: insulin resistance likely;
- <0.30: diabetes diagnosis likely.
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